Research and development institute

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Browsing Research and development institute by Subject "Antioxidant"

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    In vitro Antioxidant, Anti-Inflammatory, and Wound Healing Properties of Aloe Vera Infused with Canola Oil for Possible Application in Skin Cosmetics
    (Graphicsite 295 Nakhon Ratchasima Road, Dusit, Bangkok, Thailand 10300, 2025-04-25) Khwunjit itsarasook; Piyanuch Prompamorn; Jittarawadee Tanghiranrat; Amornrat Srisukong; Orapin Komutiban; Woraphot Haritakun; Kanlayaporn Chantree
    This research investigates the antioxidant, anti-inflammatory, and woundhealing properties of Aloe vera oil, along with its cytotoxic effects on normal human dermal fibroblasts (NHDF), particularly in the context of its potential use as a natural antioxidant in skincare formulations. A. vera oil was extracted using an infusion method with canola oil, and its properties were thorough characterized. The concentration of aloin and cycloartenol in the A. vera oil were measured using high-performance liquid chromatography (HPLC). The resulted indicated that A. vera oil exhibited no cytotoxicity towards NHDF cells. Additionally, the oil demonstrated antioxidant activity, as evidenced by its ability to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals, and its reducing potential assessed through free radical scavenging activity (FRAP) assays. Regarding its anti-inflammatory properties, the A. vera oil at a specific concentration showed no cytotoxic effects on RAW 264.7 macrophage cells. Notably, its potent anti-inflammatory effects significantly (p<0.05) reduced nitric oxide (NO) productions in RAW 264.7 macrophage cells stimulated by lipopolysaccharide (LPS), compared to the LPS-treated cells group. Moreover, NHDF cells treated with A. vera oil exhibited a statistically significant (p<0.05) improvement in wound closure area in a scratch wound assay, indicating enhanced cell migration. Collectively, these findings highlight the antioxidant, anti-inflammatory, and wound-healing properties of A. vera oil, underscoring its potential as an eco-friendly and beneficial ingredient for cosmetic skincare products.
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    The Physicochemical Properties and Consumer Acceptance of Ricegrass Beverage Ready for Consumption
    (Graphicsite, 2023-11-11) Utsaphong Uprawanna; Phitchakorn Norchai; Chananbhorn Thongrote
    Juice extracted from riceberry grass has exhibited higher phenol and antioxidant activity. The objective of this research was to enhance the value of ricegrass and to develop a product that small community enterprises can follow through the entire production process. This study was designed to examine the physicochemical, microbiological properties and sensory evaluation of ricegrass juice and ricegrass juice mixed with soybeans and navy beans (SN) milk. Rice leaves were extracted with room temperature water at ratios of 10:1, 2:1, 1:1, 1:5 and 1:10 (w/v) and with hot water at ratios of 2:1 and 1 :1 (w/v). The results revealed that ricegrass leaves extracted with room temperature water at a ratio of 1 :5 (w/v) had a higher yield, total phenol and antioxidant activity. The sensory evaluation found that 30% of ricegrass juice that was mixed with 1 0 % SN milk had the highest acceptance score on all attributes. Pasteurized products stored at 4°C for 8 days were close near to the Thai community product standard (TCPS 529/2547), but total phenol and antioxidant activity decreased during storage (p ≤ 0.05). Furthermore, ricegrass juice mixed with SN milk product is a functional drink which has plenty of phenol, antioxidant and nutrition.