Preparation and characterization of dextran-modified ZnO and Cu-doped ZnO nanohybrid material for enhanced antimicrobial delivery and activity

Simple item page
dc.contributor.authorTita Foophow
dc.contributor.authorPipat Lertkowit
dc.contributor.authorUdomsak Kitthawee
dc.contributor.authorWeerachon Phoohinkong
dc.contributor.correspondenceW. Phoohinkong; Faculty of Science and Technology, Suan Dusit University, Bangkok, 10300, Thailand; email: weerachon_pho@dusit.ac.th
dc.date.accessioned2025-03-10T07:22:48Z
dc.date.available2025-03-10T07:22:48Z
dc.date.issued2025
dc.description.abstractZinc oxide (ZnO) nanoparticles are widely used in various applications, particularly in antimicrobial products. Efforts to enhance their performance and efficacy, including copper (Cu) doping and incorporating natural polymers. In this study, dextran-modified ZnO and Cu-doped ZnO nanohybrids were synthesized and characterized using exodextran isolated from Leuconostoc mesenteroides TISTR 473. Characterization results showed that dextran binds to the surface of ZnO particles through C[sbnd]O_Zn and C-OH_O interactions, particularly at oxygen vacancy sites. The incorporation of dextran improved the antibacterial efficacy of ZnO and Cu-doped ZnO nanoparticles against bacteria related to fruit and vegetable spoilage, including gram-positive Bacillus altitudinis and gram-negative Achromobacter mucicolens. These findings highlight the potential of dextran-modified ZnO nanomaterials in enhancing antimicrobial activity and biocompatibility for biomedical applications, as well as their use in food packaging to extend shelf life. © 2024 Elsevier Ltd
dc.identifier.citationCarbohydrate Polymers
dc.identifier.doi10.1016/j.carbpol.2024.122947
dc.identifier.issn1448617
dc.identifier.scopus2-s2.0-85209106954
dc.identifier.urihttps://repository.dusit.ac.th//handle/123456789/4441
dc.languageEnglish
dc.publisherElsevier Ltd
dc.rights.holderScopus
dc.subjectAntimicrobial
dc.subjectCu-doped ZnO
dc.subjectDextran
dc.subjectFood packaging
dc.subjectNanohybrid
dc.subjectZnO
dc.titlePreparation and characterization of dextran-modified ZnO and Cu-doped ZnO nanohybrid material for enhanced antimicrobial delivery and activity
dc.typeArticle
mods.location.urlhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85209106954&doi=10.1016%2fj.carbpol.2024.122947&partnerID=40&md5=0d10117941e75a73d8efdc55206330c6
oaire.citation.volume349
Files
Collections
SCOPUS 2025