Antimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers

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dc.contributor.authorChantana Mekseepralard
dc.contributor.authorNarisa Kamkaen
dc.contributor.authorJenny M. Wilkinson
dc.contributor.correspondenceC. Mekseepralard; Department of Microbiology, Faculty of Medicine, Srinakharinwirot University, Klongtoei, Wattana, Bangkok 10110, Thailand; email: chantana@swu.ac.th
dc.date.accessioned2025-03-10T07:37:41Z
dc.date.available2025-03-10T07:37:41Z
dc.date.issued2010
dc.description.abstractFour medicinal plants (Quercus infectoria, Kaempferia galanga, Coptis chinensis and Glycyrrhiza uralensis) as well as one traditional Thai treatment for aphthous ulcers based on these four plants were tested for antimicrobial activity. MIC values for a range of bacteria and Candida albicans were determined, with both type strains and clinical isolates being used. Antioxidant activity was determined using the ABTS radical scavenging assay. Among the four plants, Q. infectoria showed antimicrobial activity against Staphylococcus aureus with an MIC of 0.41 mg/mL, while C. chinensis showed antifungal activity against C. albicans with an MIC of 6.25 mg/mL. Activity was also shown against a range of other organisms including Salmonella typhi, Serratia marcescens, Vibrio cholerae, Vibrio parahaemolyticus, Pseudomonas aeruginosa and Enterococcus faecalis. The antimicrobial activity of the traditional aphthous ulcer preparation (a powder) was comparable to that for the individual plant extracts, however, incorporation of the powder into a gel formulation resulted in the loss of almost all activity. All extracts, with the exception of K. galanga, also showed good antioxidant activity. This study supports the traditional use of these plants and suggests that they may also be useful in the treatment of other infections. © 2010 John Wiley & Sons, Ltd.
dc.identifier.citationPhytotherapy Research
dc.identifier.doi10.1002/ptr.3158
dc.identifier.issn10991573
dc.identifier.scopus2-s2.0-78649427006
dc.identifier.urihttps://repository.dusit.ac.th//handle/123456789/5045
dc.languageEnglish
dc.rights.holderScopus
dc.subjectantimicrobial activity
dc.subjectantioxidant activity
dc.subjectCoptis chinensis
dc.subjectGlycyrrhiza uralensis
dc.subjectKaempferia galanga
dc.subjectQuercus infectoria
dc.titleAntimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers
dc.typeArticle
mods.location.urlhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-78649427006&doi=10.1002%2fptr.3158&partnerID=40&md5=c0906fcfcc0a64849365f312412a19c6
oaire.citation.endPage1519
oaire.citation.issue10
oaire.citation.startPage1514
oaire.citation.volume24
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