Phytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice)

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dc.contributor.authorRittipun Rungruang
dc.contributor.authorNapassorn Peasura
dc.contributor.authorNattapon Kaisangsri
dc.contributor.correspondenceR. Rungruang; Department of Cosmetic Science, Faculty of Science and Technology, Suan Dusit University, Bangkok, 295 Nakhon Ratchasima Road, Dusit District, 10300, Thailand; email: rittipun_run@dusit.ac.th
dc.date.accessioned2025-03-10T07:35:06Z
dc.date.available2025-03-10T07:35:06Z
dc.date.issued2022
dc.description.abstractThe objective of this research was to explore the phytochemicals in Tubtim Chumphae rice bran and determine their potential antioxidant and anticancer activities. The rice bran extract contained total phenolics, flavonoids, and anthocyanins as the major compounds. In addition, it exhibited the highest DPPH¥, followed by ABTS¥+, and FRAP radical scavenging activity. Moreover, the cytotoxic effect of the extract on Hep G2, SW620, KATO-III, BT474, and ChaGo-K-1 cancer cell lines was investigated; the obtained IC50 values were 144.6 ± 0.39, 116.9 ± 0.68, 99.6 ± 0.10, 94.4 ± 0.33, and 25.6 ± 0.45 _g/mL, respectively. Overall, the abovementioned results suggest that rice bran extract has potent anticancer activity owing to the induction of cell death in cancer cell lines. © 2022 Journal of Advanced Pharmaceutical Technology & Research.
dc.identifier.citationJournal of Advanced Pharmaceutical Technology and Research
dc.identifier.doi10.4103/japtr.japtr_458_22
dc.identifier.issn22314040
dc.identifier.scopus2-s2.0-85140716015
dc.identifier.urihttps://repository.dusit.ac.th//handle/123456789/4603
dc.languageEnglish
dc.publisherWolters Kluwer Medknow Publications
dc.rights.holderScopus
dc.subjectAnticancer
dc.subjectcyanidin-3-O-glucoside
dc.subjectrice bran extract (Tubtim Chumphae rice)
dc.titlePhytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice)
dc.typeArticle
mods.location.urlhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85140716015&doi=10.4103%2fjaptr.japtr_458_22&partnerID=40&md5=74377f84a4a587420fd00923c5892b9f
oaire.citation.endPage316
oaire.citation.issue4
oaire.citation.startPage312
oaire.citation.volume13
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