SCOPUS 2010-2014

Permanent URI for this collection

https://repository.dusit.ac.th//handle/123456789/4433

Browse

Browsing SCOPUS 2010-2014 by Subject "antimicrobial activity"

Now showing 1 - 2 of 2
  • Default Image
    Item
    Antimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers
    (2010) Chantana Mekseepralard; Narisa Kamkaen; Jenny M. Wilkinson; C. Mekseepralard; Department of Microbiology, Faculty of Medicine, Srinakharinwirot University, Klongtoei, Wattana, Bangkok 10110, Thailand; email: chantana@swu.ac.th
    Four medicinal plants (Quercus infectoria, Kaempferia galanga, Coptis chinensis and Glycyrrhiza uralensis) as well as one traditional Thai treatment for aphthous ulcers based on these four plants were tested for antimicrobial activity. MIC values for a range of bacteria and Candida albicans were determined, with both type strains and clinical isolates being used. Antioxidant activity was determined using the ABTS radical scavenging assay. Among the four plants, Q. infectoria showed antimicrobial activity against Staphylococcus aureus with an MIC of 0.41 mg/mL, while C. chinensis showed antifungal activity against C. albicans with an MIC of 6.25 mg/mL. Activity was also shown against a range of other organisms including Salmonella typhi, Serratia marcescens, Vibrio cholerae, Vibrio parahaemolyticus, Pseudomonas aeruginosa and Enterococcus faecalis. The antimicrobial activity of the traditional aphthous ulcer preparation (a powder) was comparable to that for the individual plant extracts, however, incorporation of the powder into a gel formulation resulted in the loss of almost all activity. All extracts, with the exception of K. galanga, also showed good antioxidant activity. This study supports the traditional use of these plants and suggests that they may also be useful in the treatment of other infections. © 2010 John Wiley & Sons, Ltd.
  • Default Image
    Item
    Chemical composition, antibacterial and antifungal activities of essential oil from Heracleum Siamicum Craib
    (2011) T. Kuljanabhagavad; N. Sriubolmas; N. Ruangrungsi; N. Ruangrungsi; Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand; email: rnijsiri@chula.ac.th
    Heracleum siamicum Craib (Apiaceae), is an important herbal species having wide application in food flavoring processes. The flat-oval shaped fruit of H. siamicum Craib from North Thailand was hydrodistilled, and the chemical composition of the essential oil was analyzed by GC and GC-MS. The essential oil yield based on dried plant material was 1.25%, and twenty-five compounds (corresponding to 97.69% of the total weight) were identified. The main components were: n-octyl acetate (65.30%), o-cymene (10.35%), limonene (7.52%), _-2-carene (6.87%), cis-thujone (1.92%), isobornyl acetate (0.94%), n-octanol (0.73%), 1,8-cineol (0.62%), n-tridecanol (0.44%), and safrole (0.37%). H. siamicum essential oil demonstrated bactericidal and fungicidal activity against five bacterial strains and two fungal strains, as evaluated using agar diffusion in terms of the minimum inhibitory concentration. © 2011 Springer Science+Business Media, Inc.