Browsing by Author "Nartlada Onvimol"

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    Antimicrobial Effect of Deodorant Products Containing Rhinacanthus nasutus Extract for Reducing Armpit Odor
    (Research and Development Institute Suan Dusit University, 2022) Nartlada Onvimol; Rittipun Rungruang; Surapha Modsuwan; Tasanee Panichakul; T. Panichakul; Faculty of Science and Technology, Suan Dusit University, Bangkok, 10700, Thailand; email: tasanee_p@yahoo.com
    The aim of this study was to investigate the effectiveness of developing a roll-on deodorant that can reduce armpit microbiota bacteria to decrease armpit odor. The richest apocrine sweat glands in the armpit region secrete a variety of odor precursors that are transformed into volatile odoriferous substances by bacterial enzymes on the skin surface. The dominant armpits microbiota included four groups of bacteria such as Staphylococcus spp., Micrococcus spp., Corynebacterium spp., and Propionibacterium spp., and also fungi or yeasts. Two formulas of the roll-on deodorant products, RDEOF-1 and RDEOF-2 were developed. RDEOF-2 contained an ethanolic extract of Rhinacanthus nasutus (L.) Kurz leaves inhibited several microorganisms, including Gram-positive and Gram-negative bacteria. Sixteen healthy volunteers showed satisfactory assessment for RDEOF-2 that was greater than RDEOF-1. Armpit bacteria were collected by swab method and armpit odor was evaluated by ASTM method. Results showed dominant bacteria of two genera including Staphylococcus spp. and Corynebacterium spp. in all swab samples that mainly cause armpit odor. Armpit bacterial numbers before using deodorants were high in the range of 2x103 to 9x105 (CFU/mL). After applying RDEOF-1 and RDEOF-2, bacterial numbers decreased in the range of 1x103 to 8x105 and 3x102 to 4x105 (CFU/mL), respectively. Armpit bacteria were found in males more than in females. Deodorant products containing R. nasutus extract have been shown to reduce the bacteria that cause armpit odor. Therefore, the development of the deodorant product with natural plant extracts is warranted. © 2022, Research and Development Institute Suan Dusit University. All rights reserved.
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    Antimicrobial Effect of Deodorant Products Containing Rhinacanthus nasutus Extract for Reducing Armpit Odor
    (Graphicsite, 2023-09-26) Nartlada Onvimol; Rittipun Rungruang; Surapha Modsuwan; Tasanee Panichakul
    The aim of this study was to investigate the effectiveness of developing a roll-on deodorant that can reduce armpit microbiota bacteria to decrease armpit odor. The richest apocrine sweat glands in the armpit region secrete a variety of odor precursors that are transformed into volatile odoriferous substances by bacterial enzymes on the skin surface. The dominant armpits microbiota included four groups of bacteria such as Staphylococcus spp., Micrococcus spp., Corynebacterium spp., and Propionibacterium spp., and also fungi or yeasts. Two formulas of the roll-on deodorant products, RDEOF-1 and RDEOF-2 were developed. RDEOF-2 contained an ethanolic extract of Rhinacanthus nasutus (L.) Kurz leaves inhibited several microorganisms, including Gram-positive and Gram-negative bacteria. Sixteen healthy volunteers showed satisfactory assessment for RDEOF-2 that was greater than RDEOF-1. Armpit bacteria were collected by swab method and armpit odor was evaluated by ASTM method. Results showed dominant bacteria of two genera including Staphylococcus spp. and Corynebacterium spp. in all swab samples that mainly cause armpit odor. Armpit bacterial numbers before using deodorants were high in the range of 2x103 to 9x105 (CFU/mL). After applying RDEOF-1 and RDEOF-2, bacterial numbers decreased in the range of 1x103 to 8x105 and 3x102 to 4x105 (CFU/mL), respectively. Armpit bacteria were found in males more than in females. Deodorant products containing R. nasutus extract have been shown to reduce the bacteria that cause armpit odor. Therefore, the development of the deodorant product with natural plant extracts is warranted.
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    Evaluation of Antimicrobial Activity of Rhinacanthus nasutus (L.) Kurz and Acanthus ilicifolius L. Extracts
    (Research and Development Institute Suan Dusit University, 2021) Nartlada Onvimol; Napa Onvimala; Nattaporn Boohuad; N. Onvimol; Faculty of Science and Technology, Suan Dusit University, Bangkok, 10700, Thailand; email: nartlada_onv@dusit.ac.th
    The aim of this research was to evaluate the antimicrobial properties of medical plants Rhinacanthus nasutus (L.) Kurz and Acanthus ilicifolius L. that were extracted with water/aqueous (AqER, AqEA) and ethanol (EtER, EtEA). The extracts were tested for activity and evaluated based on the effectiveness against three strains of microorganism: Gram-positive bacteria such as Staphylococcus aureus, Gram-negative bacteria such as Escherichia coli, and fungal such as Candida albicans by using the agar well diffusion and broth dilution method. The extracts from Rhinacanthus nasutus and Acanthus ilicifolius with ethanol showed the effect of inhibiting all microbes. The most effective against Candida albicans with the similar MIC and MFC values of 18.75 and 37.50 mg/mL. Meanwhile, extracts with water of Rhinacanthus nasutus and Acanthus ilicifolius with MIC values of 37.50 and 75 mg/mL and MFC values of 75 and 150 mg/mL, respectively. Conversely, these extracts showed no effect to inhibit Escherichia coli. This could be due to the capabilities of the solvents extractive and using part of the plant. Likewise, a combination of the extracts with ethanol of R. nasutus and A. ilicifolius to evaluate the efficacy of synergistic herbs can be considered from the MIC value. The antimicrobial synergy was evaluated in terms of FIC obtained from multiple-combination bactericidal/fungicidal assays. FICi value was interpreted as synergy only in ethanol extract R. nasutus+A. ilicifolius (EtRA) of 0.26. © 2021, Research and Development Institute Suan Dusit University. All rights reserved.
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    Evaluation of Antimicrobial Activity of Rhinacanthus nasutus (L.) Kurz and Acanthus ilicifolius L. Extracts
    (Graphicsite, 2023-09-26) Nartlada Onvimol; Napa Onvimala; Nattaporn Boohuad
    The aim of this research was to evaluate the antimicrobial properties of medical plants Rhinacanthus nasutus (L.) Kurz and Acanthus ilicifolius L. that were extracted with water/aqueous (AqER, AqEA) and ethanol (EtER, EtEA). The extracts were tested for activity and evaluated based on the effectiveness against three strains of microorganism: Gram-positive bacteria such as Staphylococcus aureus, Gram-negative bacteria such as Escherichia coli, and fungal such as Candida albicans by using the agar well diffusion and broth dilution method. The extracts from Rhinacanthus nasutus and Acanthus ilicifolius with ethanol showed the effect of inhibiting all microbes. The most effective against Candida albicans with the similar MIC and MFC values of 18.75 and 37.50 mg/mL. Meanwhile, extracts with water of Rhinacanthus nasutus and Acanthus ilicifolius with MIC values of 37.50 and 75 mg/mL and MFC values of 75 and 150 mg/mL, respectively. Conversely, these extracts showed no effect to inhibit Escherichia coli. This could be due to the capabilities of the solvents extractive and using part of the plant. Likewise, a combination of the extracts with ethanol of R. nasutus and A. ilicifolius to evaluate the efficacy of synergistic herbs can be considered from the MIC value. The antimicrobial synergy was evaluated in terms of FIC obtained from multiple-combination bactericidal/fungicidal assays. FICi value was interpreted as synergy only in ethanol extract R. nasutus+A. ilicifolius (EtRA) of 0.26.